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Cephalosporin antibiotics

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Janssen Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. (Johnson & Johnso

Cephalosporin antibiotics are often used to treat common bacterial infections and commonly used for surgical prophylaxis.

To make the process of creating cephalosporin's more environmentally sustainable; the synthesis steps in the creation process have been reduced by 50% (from 8 to 4). The yield has been nearly tripled (from 12% to 34%) and there has been an 80% reduction of hazardous solvents. As a result, the creation process is safer, waste streams are significantly reduced, shorter cycle times are obtained, and drug substance quality is improved.

Johnson & Johnson

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